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Hyperbaric Oxygen for Autism

Posted in Neurologica by Skepdude on March 16, 2009

A new study looks at the effectiveness of hyperbaric oxygen therapy in autism. The study is the first double-blind placebo controlled study of such therapy in autism and found a significant improvement in those children in the treatment group.

However, the treatment is very controversial and remains so, even after this study.

Hyperbaric oxygen therapy involves placing patients in a chamber with pressure increased above atmospheric pressure with an enriched oxygen content.  It has many legitimate medical applications, such as treating certain kinds of infection, but also has become popular among some as an unscientific treatment. It is offered by practitioners and chambers are even sometimes purchased by private individuals for their own family’s use.

The problem, of course, is that some claims for hyperbaric oxygen go way past the evidence, or exist in the utter absence of evidence. This includes autism – there are no compelling studies showing any benefit from hyperbaric oxygen therapy in autism. The few studies that do exist are uncontrolled, which means they are mostly worthless.

This current study is at least a double-blind controlled trial. But it still has significant weaknesses. The primary weakness, in my opinion, is that the parents of the children being studied were allowed in the chamber with their children. The two groups in the study either received 24% oxygen in 1.3 atmospheres, or 21% oxygen in 1.03 atmospheres. It’s probable that many of the parents knew if they were getting increased pressure or not, and this therefore could have unblinded the study.

Tight blinding is critical for these type of studies because the assessment of the effect on the autistic children is highly subjective. For example, the assessment includes how much eye contact the children make.

READ THE REST OF THIS ENTRY AT “NEUROLOGICA”

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One Response

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  1. Magdalena said, on August 1, 2013 at 11:42 PM

    You really make it seem so easy with your presentation but I find this topic to be really something
    that I think I would never understand. It seems too complicated and
    extremely broad for me. I am looking forward for your
    next post, I’ll try to get the hang of it!


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